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This is because hemoglobin A1C (a measure of blood sugar control) and sex hormone-binding globulin (SHBG) are inversely correlated: as A1C improves with weight loss, SHBG levels may rise, which can bind more testosterone and reduce the amount that circulates freely in the bloodstream
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[DOI] [PubMed] [Google Scholar] 119.Vidal-Rohr M, Craig JP, Davies LN, Wolffsohn JS
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